ceesdekker.net - An Overview
ceesdekker.net - An Overview
Blog Article
Midway as a result of his vocation, Cees Dekker reinvented himself. After decades of hardcore physics, he shifted his emphasis to ‘nanobiology’ on the transform with the millennium. A phrase he coined himself, to be a issue of simple fact.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
As a human being, I hold the biblical assignment to take a look at and use every little thing in creation for the advantage of my neighbour. I will not knowledge any conflict concerning religion and science. On the contrary, my faith stimulates me to perform science, being open up-minded on the planet.’
Nanofabrication of electrodes with sub-5 nm spacing for transport experiments on one molecules and steel clusters
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart design and style in 2005. (nl)
Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim with the pore is highlighted in crimson, along with a 3D rendering of your motion of your DNA rod is shown.
What distinguishes biology from chemistry is the fact that these factors collectively make up a dwelling program. The trick of mentioned everyday living, I believe, lies during the interactions, the interplay of All those molecules. The big concern about the origin of lifestyle remains to be unanswered. How did we at any time evolve from straightforward molecules into your very advanced methods we see nowadays? We do not know. I want to operate on These types of big, open issues.’
Nanopores depict a chic and adaptable Device to measure solitary molecules. We analysis novel detection modes with sound-condition nanopores along with numerous methods to measure proteins with nanopores. Projects encompass the subsequent:
2003, shown the 1st biosensors designed away from a carbon nanotube; settled the structure and system of DNA repair service proteins; and discovery of a different strategy for fabricating sound-state nanopores for DNA translocation
one). The current–voltage curves showed sizeable modulations with gate voltage, even at area temperature, which was consistent with band bending in the ~0.6 eV bandgap semiconducting nanotube. These knowledge also confirmed the conductance can be modulated by six orders of magnitude by transforming the gate voltage. The outcomes of the work — a area-temperature transistor made from an individual carbon nanotube molecule — were being printed in Character in May 1998.
view Share your interactive ePaper on all platforms and on your web site with our embed functionality
Mother nature Physics thanks the nameless reviewers for their contribution to the peer critique of this do the job.
One example is, we consider the nucleopore sophisticated, a gateway in between the mobile nucleus as well as cytoplasm. This is an extremely difficult system and as a consequence challenging to examine inside a mobile, so we use biomimetics. We reconstruct holes then insert personal components of your nucleopore intricate to study transportation by means of it at the single-molecule stage.’
It had been an exceedingly intriguing time, through which I received a great deal of aid from Delft University of Technological innovation, ceesdekker.net where by I was a professor at time, And that i begun a number of collaborations with molecular biologists. That assisted me study a lot.’